Dying to reproduce: Ageing through reproductive death in Caenorhabditis elegans

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Slide1

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28th October @ 2pm

The nematode Caenorhabditis elegans has been widely used as a model organism to study ageing, particularly since the discovery that single gene mutations can dramatically increase its lifespan. Results presented in this talk, however, suggest that C. elegans exhibit reproductive death similar to Pacific salmon, suppression of which provides a potential explanation for the unusually large magnitude of lifespan extension seen in C. elegans. This account in certain respects explains away the mystique of C. elegans ageing. It also has major implications in terms of what one can learn about human ageing from C. elegans.