Recent technological advances are allowing scientists to redesign organisms or even build new life forms from scratch. This new developing area of research steps beyond traditional Genetic Modification (GM), to combine science and engineering in what is known as Synthetic Biology.
Technologies such as CRISPR-Cas are already allowing us to apply GM to a wide range of fields, from pest control to human genome editing. But these potential practical applications are huge, such as bioengineered micromachines/microorganisms that can destroy cancer cells, detect toxic chemicals or produce drugs that are otherwise incredibly difficult to obtain from nature.
Is society ready for this new discipline? Where should the limits be set? What are the benefits and the risks of these “by-design” organisms?
Four prominent researchers specialised in Synthetic Biology from different backgrounds will discuss these and other pressing questions in our annual debate organised in association with the Linnean Society.
Date: 19th April 2018, from 5.30pm
Venue: The Linnean Society of London, Burlington House, Piccadilly, London, W1J 0BF, United Kingdom
The event is free and open to all but registration is essential. Seats will be allocated on a first-come, first-served basis.
Follow this link to register
Stay tuned for further updates!
Speaker: Dr. Andrea Dixon (Rothamsted)
Title: At the edge of the species: the effects of gene flow on fitness
Where: Medawar Building G02 Watson LT, UCL (Gower Street, London, WC1E 6BT)
When: 25th April 2017, 18:30
Species ranges that are distributed across environmentally heterogeneous landscapes can be constrained by the efficacy of natural selection at range edges. Constraints on adaptation in range edge populations may arise because of small effective population size or because of an antagonism between divergent selection and gene flow. Mimulus bicolor, is an herbaceous spring annual constrained to the Sierra Nevada Mountain range in California, USA. To understand if maladaptive gene flow or small effective population size limits the species’ range, we investigated if populations found at climatically divergent range edges and at the center of the range were locally adapted using a common garden experiment in climate-controlled chambers. We then assessed the consequences of gene flow into edge populations by comparing the fitness of hybrids to parents originating from the local edge environment. These common garden analyses were supported by coalescent analysis to estimate effective population size and gene flow between central and edge populations originating from the field. From the common garden experiment, our results suggest that the populations used in this study were not locally adapted and gene flow from central to edge populations increased hybrid fitness. In addition, edge populations were effectively smaller than central populations. Taken together, these results reject the hypothesis that the range limits reflect an antagonism between divergent selection and gene flow. The geographic distribution of M. bicolor, however, likely reflects the reduced efficacy of natural selection in effectively small populations inhabiting stressful range edge environments.
Leadership serves the need for coordination and direction in social groups of many species, and for humans it has special properties and significance. We notice when it fails more than when it succeeds, and it has been heavily and largely poorly theorised in the business literature. We shall discuss why this is and how an evolutionary perspective can help us understand the preconditions, from a practical and theoretical standpoint, for its success and failure as an adaptive instrument for groups and institutions.
NEW! Programme and abstracts book available here: lern2016_abstract_book.pdf
Our annual conference is coming up! Join us for a great day of discovering the great evolutionary research being done by fellow students and PostDocs from around London and beyond!
Please register here. If you’d like to submit an abstract for a 15 minute talk, lightning talk, or poster, please email us at firstname.lastname@example.org.
As usual in the last few years, we have a theme for our keynote speakers: the Application of Evolutionary Principles to Agriculture and Medicine.
More information here.
When: 9th November 2016
Location: Fogg lecture theater, Queen Mary University
Accessibility: The Fogg Lecture Theatre is wheelchair-accessible. There is easy access to a wheelchair-accessible toilet.